El Jefe Desert Cantina

Inside, the atmosphere and design is signature Saguaro: bold, relaxed, and brimming with uncomplicated fun. But don’t let the oversized mural of four floatie-adorned luchadores— or the ‘80s video games doubling as drink tables—lead you to believe you’ll find anything less than seriously-thoughtful craft cocktails at the bar. Anchored by a collection of agave-based spirits, the menu features nearly 20 unique cocktails for fans of seasonal and classic mezcal and tequila drinks. Try El Jefe’s The Floor is Guava—made with Fresno chili-infused tequila blanco and pink guava—or choose a mezcal riff on something more familiar, like the Mezcal Old Fashioned or Mezcal Negroni.